Okay guys, have an update! While Ron works on a more permanent 1 cable solution in the software (and Ron if you are ever in Washington, give me a ring, beer is on me for all the hard work you put in) I found a way to get things up and running...
This solution requires your normal USB 2.0 cable to connect to the PBC and some sort of midi interface. I used an M-Audio Uno USB to midi interface. I'm sure you could also use an audio interface that has Midi I/O included.
It's fairly simple on the software side. You need to go to the Midi tab on the PBC Editor and enable "Midi Merge". This basically allows you to send midi information from the Strymon App through the USB cable then converts the signal to midi on the midi out of the PBC.
As usaual you string your midi devices together. But on the last midi out (for me it's my Big Sky) I connect the Midi Out of the midi USB interface to the Midi Out of the Big Sky or whatever is last in your chain.
So, you do not connect the Midi IN of the midi interface to the PBC input, only connect the midi interface to the output of your last pedal in the chain.
The genius here is that Ron allowed the PBC to act as a converter on the MIDI send and change USB to Midi on the output Midi of the PBC. I tried connecting the Midi send to the input of the PBC and the pedals did not like it. It created a midi feedback loop like I thought and the Strymon App was competing between the send of the PBC USB-Midi against the Midi interface.
This method seems to work for me and I have all three Strymon Units working and syncing to Nixie. Give it a try!